In honor of World AIDS Day and the 10th anniversaries of AIDS charities ONE and (RED) on Tuesday (Dec. 1), a bunch of big stars made their way to New York City's famed Carnegie Hall. U2 frontman Bono, co-founder of both organizations, performed alongside the Edge, while The Daily Show host Trevor Noah emceed and Stephen Colbert, Joe Biden and a bunch of other really famous people were there. Jessie J and Miley Cyrus also performed, taking the stage with Bono for the U2 classic "One."

If only it was that easy. Miley reportedly missed her cue and had to ask Bono for help. Check it out in the video above, around the 2:00 minute mark.

It's hard to make out, but it sounds like Cyrus' mouthed, "You gotta help me" and Bono continues to carry the tune. If she was just asking for a helping hand or a lifeline, we're sure it was a powerful performance.

When you're done trying to figure that one out, click through our list of the most memorable VMA moments of all time. Familiar faces abound!